Amitriptyline
Product Specifications
CAS Number
50-48-6
Synonyms
MK-230, N-750, Ro41575
Target
5-HT Receptor
Applications
Neuronal Signaling
Smiles
CN (C) CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31
Molecular Formula
C20H23N
Additionnal Information
Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties, widely used to treat depression and neuropathic pain. Amitriptyline is an inhibitor of both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. Amitriptyline also inhibits histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. This product is a waxy solid.
Storage Conditions
2 years -20°C liquid
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15359959 1 Vial
Lentiviral human SLC25A3 sgRNA gene knockout kit - Lentiviral human SLC25A3 sgRNA gene knockout kit (100)
Sign In for Pricing
View Details 
GTR15241203 1 Vial
Lentiviral mouse Grin2d shRNA (UAS) - Lentiviral mouse Grin2d shRNA (UAS, iRFP) (100)
Sign In for Pricing
View Details ![(4R) -3-[ (2S) -2-[ (S) -[4-[[ (1,1-Dimethylethyl) dimethylsilyl]oxy]phenyl][ (4-fluorophenyl) amino]methyl]-4-[2- (4-fluorophenyl) -5,5-dimethyl-1,3-dioxan-2-yl]-1-oxobutyl]-4-phenyl-2-oxazolidinone](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
434129-01 10 mg
(4R) -3-[ (2S) -2-[ (S) -[4-[[ (1,1-Dimethylethyl) dimethylsilyl]oxy]phenyl][ (4-fluorophenyl) amino]methyl]-4-[2- (4-fluorophenyl) -5,5-dimethyl-1,3-dioxan-2-yl]-1-oxobutyl]-4-phenyl-2-oxazolidinone
Sign In for Pricing
View Details 434129-02 25 mg
(4R) -3-[ (2S) -2-[ (S) -[4-[[ (1,1-Dimethylethyl) dimethylsilyl]oxy]phenyl][ (4-fluorophenyl) amino]methyl]-4-[2- (4-fluorophenyl) -5,5-dimethyl-1,3-dioxan-2-yl]-1-oxobutyl]-4-phenyl-2-oxazolidinone
Sign In for Pricing
View Details