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JANEX-1

Product Specifications

CAS Number

202475-60-3

Synonyms

WHI-P131

Target

JAK

Applications

Angiogenesis

Smiles

COC1=C (C=C2C (=C1) C (=NC=N2) NC3=CC=C (C=C3) O) OC

Molecular Formula

C16H15N3O3

Additionnal Information

JANEX-1 (WHI-P131) is a small molecule inhibitor of JAK3 that selectively inhibits JAK3 at an IC50 of 78 μM without altering the activity of JAK1 or JAK2, or any other protein tyrosine kinases (IC50 ≥ 350 μM) .

Storage Conditions

3 years -20°C powder

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