Acalisib (GS-9820)
Product Specifications
CAS Number
870281-34-8
Synonyms
CAL-120
Target
PI3K
Applications
PI3K/Akt/mTOR
Smiles
CC (C1=NC2=C (C=C (C=C2) F) C (=O) N1C3=CC=CC=C3) NC4=NC=NC5=C4NC=N5
Molecular Formula
C21H16FN7O
Additionnal Information
Acalisib (GS-9820, CAL-120) is a highly selective and potent p110δ inhibitor (IC50 = 14 nM) with 114- to 400-fold selectivity over the other class I PI3K enzymes and no activity against Class II and III PI3K family members or other PI3K-related proteins including mTOR and DNA-PK.
Storage Conditions
3 years -20°C powder
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