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Acalisib (GS-9820)

Product Specifications

CAS Number

870281-34-8

Synonyms

CAL-120

Target

PI3K

Applications

PI3K/Akt/mTOR

Smiles

CC (C1=NC2=C (C=C (C=C2) F) C (=O) N1C3=CC=CC=C3) NC4=NC=NC5=C4NC=N5

Molecular Formula

C21H16FN7O

Additionnal Information

Acalisib (GS-9820, CAL-120) is a highly selective and potent p110δ inhibitor (IC50 = 14 nM) with 114- to 400-fold selectivity over the other class I PI3K enzymes and no activity against Class II and III PI3K family members or other PI3K-related proteins including mTOR and DNA-PK.

Storage Conditions

3 years -20°C powder

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