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GSK0660

Product Specifications

CAS Number

1014691-61-2

Target

PPAR

Applications

DNA Damage/DNA Repair

Smiles

COC1=C (C=CC (=C1) NC2=CC=CC=C2) NS (=O) (=O) C3=C (SC=C3) C (=O) OC

Molecular Formula

C19H18N2O5S2

Additionnal Information

GSK0660 is a potent PPARβ/δ antagonist with a pIC50 of 6.8 (binding assay IC50 = 155 nM; antagonist assay IC50 = 300 nM) and is nearly inactive on PPARα and PPARγ with IC50s above approximately 10 μM.

Storage Conditions

3 years -20°C powder

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