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HMN-176

Product Specifications

CAS Number

173529-10-7

Target

PLK

Applications

Cell Cycle

Smiles

COC1=CC=C (C=C1) S (=O) (=O) N=C2C=CC=CC2=CC=C3C=CN (C=C3) O

Molecular Formula

C20H18N2O4S

Additionnal Information

HMN-176 is an active metabolite of HMN-214, which has a potent antitumor activity in mouse xenograft models. HMN-176 effectively inhibits PLK-1 by interference with its normal subcellular spatial distribution at centrosomes and along the cytoskeletal structure.

Storage Conditions

3 years -20°C powder

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