Quetiapine
Product Specifications
CAS Number
111974-69-7
Synonyms
ICI204636
Target
5-HT Receptor
Applications
Neuronal Signaling
Smiles
C1CN (CCN1CCOCCO) C2=NC3=CC=CC=C3SC4=CC=CC=C42
Molecular Formula
C21H25N3O2S
Additionnal Information
Quetiapine (ICI204636) is an atypical antipsychotic used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder.Quetiapine is a 5-HT receptors agonist with a pEC50 of 4.77 for human 5-HT1A receptor. Quetiapine is a dopamine receptor antagonist with a pIC50 of 6.33 for human D2 receptor. Quetiapine have moderate to high affinity for the human D2, HT1A, 5-HT2A, 5-HT2C receptor with pKis of 7.23, 5.74, 7.54, 5.55.
Storage Conditions
3 years -20°C powder
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