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Lurasidone

Product Specifications

CAS Number

367514-87-2

Synonyms

SM-13496

Target

Dopamine Receptor

Applications

Neuronal Signaling

Smiles

C1CCC (C (C1) CN2CCN (CC2) C3=NSC4=CC=CC=C43) CN5C (=O) C6C7CCC (C7) C6C5=O

Molecular Formula

C28H36N4O2S

Additionnal Information

Lurasidone (SM-13496) is a second-generation antipsychotic agent that exhibits full antagonism at dopamine D2 and serotonin 5-HT2A receptors with binding affinities Ki = 1 nM and Ki = 0.5 nM, respectively. It also has high affinity for serotonin 5-HT7 receptors (Ki = 0.5 nM), partial agonist activity at 5-HT1A receptors (Ki = 6.4 nM) and lacks affinity for histamine H1 and muscarinic M1 receptors.

Storage Conditions

3 years -20°C powder

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