Bedaquiline
Product Specifications
CAS Number
843663-66-1
Synonyms
TMC-207, R207910
Target
ATPase
Applications
Transmembrane Transporters
Smiles
CN (C) CCC (C1=CC=CC2=CC=CC=C21) (C (C3=CC=CC=C3) C4=C (N=C5C=CC (=CC5=C4) Br) OC) O
Molecular Formula
C32H31BrN2O2
Additionnal Information
Bedaquiline (TMC-207, R207910), a diarylquinoline, binds to subunit c of mycobacterial ATP synthase and inhibits its activity. It is highly selective for mycobacterial ATP synthase enzyme compared to homologous eukaryotic enzyme (Selectivity Index >20 000) .
Storage Conditions
3 years -20°C powder
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