Dasabuvir (ABT-333)
Product Specifications
CAS Number
1132935-63-7
Target
HCV Protease
Applications
Proteases
Smiles
CC (C) (C) C1=CC (=CC (=C1OC) C2=CC3=C (C=C2) C=C (C=C3) NS (=O) (=O) C) N4C=CC (=O) NC4=O
Molecular Formula
C26H27N3O5S
Additionnal Information
Dasabuvir (ABT-333) is a non-nucleoside inhibitor of NS5B viral RNA-dependent RNA polymerase that inhibits recombinant NS5B polymerases derived from HCV genotype 1a and 1b clinical isolates with IC50 values between 2.2 and 10.7 nM. It is at least 7,000-fold selective for the inhibition of HCV genotype 1 polymerases over human/mammalian polymerases.
Storage Conditions
2 years -80 in solvent
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