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2-Acetylphenothiazine (ML171)

Product Specifications

CAS Number

6631-94-3

Synonyms

2-APT

Target

NADPH-oxidase

Applications

Immunology & Inflammation

Smiles

CC (=O) C1=CC2=C (C=C1) SC3=CC=CC=C3N2

Molecular Formula

C14H11NOS

Additionnal Information

2-Acetylphenothiazine (ML171, 2-APT) is a potent and selective inhibitor of NADPH-oxidase with IC50s of 0.25 μM, 5 μM, 3μM, 5 μM and 5.5 μM for NOX1, NOX2, NOX3, NOX4 and xanthine oxidase, respectively.

Storage Conditions

2 years -80 in solvent

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