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Toceranib phosphate

Product Specifications

CAS Number

874819-74-6

Synonyms

Palladia, SU11654

Target

VEGFR

Applications

Protein Tyrosine Kinase

Smiles

CC1=C (NC (=C1C (=O) NCCN2CCCC2) C) C=C3C4=C (C=CC (=C4) F) NC3=O.OP (=O) (O) O

Molecular Formula

C22H25FN4O2.H3O4P

Additionnal Information

Toceranib phosphate (Palladia, SU11654), the phosphate salt of toceranib, is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family, including Flk-1/KDR, PDGFR, and Kit with Ki values of 6 nM and 5 nM for Flk-1/KDR and PDGFRβ, respectively.

Storage Conditions

3 years -20°C powder

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