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Apatinib

Product Specifications

CAS Number

811803-05-1

Synonyms

Rivoceranib, YN968D1

Target

VEGFR

Applications

Protein Tyrosine Kinase

Smiles

O=C (NC1=CC=C (C=C1) C2 (CCCC2) C#N) C3=C (NCC4=CC=NC=C4) N=CC=C3

Molecular Formula

C24H23N5O

Additionnal Information

Apatinib (Rivoceranib, YN968D1) is a potent inhibitor of the VEGF signaling pathway with IC50 values of 1 nM, 13 nM, 429 nM and 530 nM for VEGFR-2, Ret (c-Ret), c-Kit and c-Src, respectively. Apatinib induces both autophagy and apoptosis.

Storage Conditions

3 years -20°C powder

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