What is the catalog number for Ruxolitinib Phosphate?

The catalog number for Ruxolitinib Phosphate is C10838-25mg.

What sizes are available for Ruxolitinib Phosphate?

Ruxolitinib Phosphate is available in the following size(s): 25 mg.

Is Ruxolitinib Phosphate in stock?

Ruxolitinib Phosphate is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Ruxolitinib Phosphate?

Ruxolitinib Phosphate is requires dry ice shipping.

Ruxolitinib Phosphate

Product Specifications

CAS Number

1092939-17-7

Synonyms

INCB018424, INC424

Target

JAK

Applications

Angiogenesis

Smiles

C1CCC (C1) C (CC#N) N2C=C (C=N2) C3=C4C=CNC4=NC=N3.OP (=O) (O) O

Molecular Formula

C17H18N6.H3O4P

Additionnal Information

Ruxolitinib Phosphate (INCB018424, INC424) is the phosphate salt form of Ruxolitinib. Ruxolitinib is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3. Ruxolitinib kills tumor cells through toxic mitophagy. Ruxolitinib induces autophagy and enhances apoptosis.