Fenretinide

Product Specifications

CAS Number

65646-68-6

Synonyms

NSC 374551, 4-hydroxy (phenyl) retinamide, 4-HPR, MK-4016

Target

Retinoid Receptor

Applications

Metabolism

Smiles

CC1=C (C (CCC1) (C) C) C=CC (=CC=CC (=CC (=O) NC2=CC=C (C=C2) O) C) C

Molecular Formula

C26H33NO2

Additionnal Information

Fenretinide is a synthetic derivative of retinoic acid that has a broad-spectrum of cytotoxic activity against primary tumor cells, cell lines, and/or xenografts of various cancers (including neuroblastoma) . Fenretinide (4-hydroxy (phenyl) retinamide; 4-HPR) is a synthetic derivative of retinoic acid, fenretinide can bind to retinoic acid receptor (RAR) and retinoid X receptor (RXR) at concentrations necessary to induce cell death.