Dabrafenib Mesylate
Product Specifications
CAS Number
1195768-06-9
Synonyms
GSK2118436 Mesylate
Target
Raf
Applications
MAPK
Smiles
CC (C) (C) C1=NC (=C (S1) C2=NC (=NC=C2) N) C3=C (C (=CC=C3) NS (=O) (=O) C4=C (C=CC=C4F) F) F.CS (=O) (=O) O
Molecular Formula
C23H20F3N5O2S2.CH4O3S
Additionnal Information
Dabrafenib Mesylate (GSK2118436) is the mesylate salt form of dabrafenib, an orally bioavailable inhibitor of B-raf (BRAF) protein with IC50s of 0.8 nM, 3.2 nM and 5 nM for B-Raf (V600E), B-Raf (WT) and C-Raf, respectively.
Storage Conditions
3 years -20°C powder
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