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Irinotecan hydrochloride

Product Specifications

CAS Number

100286-90-6

Synonyms

CPT-11 hydrochloride, (+) -Irinotecan hydrochloride

Target

Topoisomerase

Applications

DNA Damage/DNA Repair

Smiles

Cl.CCC1=C2CN3C (=O) C4=C (C=C3C2=NC5=C1C=C (OC (=O) N6CCC (CC6) N7CCCCC7) C=C5) C (O) (CC) C (=O) OC4

Molecular Formula

C33H39ClN4O6

Additionnal Information

Irinotecan (CPT-11, (+) -Irinotecan) hydrochloride is an inhibitor of Topoisomerase I (Topo I) that exhibits cytotoxicity in LoVo cells and HT-29 cells with IC50 of 15.8 μM and 5.17 μM, respectively.

Storage Conditions

3 years -20°C powder

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