What is the catalog number for Tacrolimus (FK506)?

The catalog number for Tacrolimus (FK506) is C10622-10mM/1mL.

What sizes are available for Tacrolimus (FK506)?

Tacrolimus (FK506) is available in the following size(s): 10 mM/1mL.

Is Tacrolimus (FK506) in stock?

Tacrolimus (FK506) is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Tacrolimus (FK506)?

Tacrolimus (FK506) is requires dry ice shipping.

Tacrolimus (FK506)

Product Specifications

CAS Number

104987-11-3

Synonyms

FR900506, Fujimycin

Target

Phosphatase

Applications

Metabolism

Smiles

CC1CC (C2C (CC (C (O2) (C (=O) C (=O) N3CCCCC3C (=O) OC (C (C (CC (=O) C (C=C (C1) C) CC=C) O) C) C (=CC4CCC (C (C4) OC) O) C) O) C) OC) OC

Molecular Formula

C44H69NO12

Additionnal Information

Tacrolimus (FK506) is a 23-membered macrolide lactone, it reduces peptidyl-prolyl isomerase activity in T cells by binding to the immunophilin FKBP12 (FK506 binding protein) creating a new complex. Tacrolimus also inhibits the phosphatase activity of calcineurin. Tacrolimus induces vascular endothelial autophagy.