What is the catalog number for Ceritinib dihydrochloride?

The catalog number for Ceritinib dihydrochloride is C10586-5mg.

What sizes are available for Ceritinib dihydrochloride?

Ceritinib dihydrochloride is available in the following size(s): 5 mg.

Is Ceritinib dihydrochloride in stock?

Ceritinib dihydrochloride is currently made to order / not held in immediate stock. Contact us for lead time.

Ceritinib dihydrochloride

Product Specifications

CAS Number

1380575-43-8

Synonyms

Zykadia, LDK378 dihydrochloride

Target

ALK

Applications

Protein Tyrosine Kinase

Smiles

Cl.Cl.CC (C) OC1=C (NC2=NC=C (Cl) C (=N2) NC3=CC=CC=C3[S] (=O) (=O) C (C) C) C=C (C) C (=C1) C4CCNCC4

Molecular Formula

C28H38Cl3N5O3S

Additionnal Information

Ceritinib (Zykadia, LDK378) dihydrochloride is a selective, orally bioavailable and ATP-competitive inhibitor of ALK with IC50 of 0.2 nM. Ceritinib dihydrochloride also inhibits InsR, IGF-1R and STK22D with IC50 of 7 nM, 8 nM and 23 nM, respectively. Ceritinib exhibits antitomor activity.