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Regorafenib Hydrochloride

Product Specifications

CAS Number

835621-07-3

Synonyms

Stivarga, BAY 73-4506 hydrochloride

Target

VEGFR

Applications

Protein Tyrosine Kinase

Smiles

Cl.CNC (=O) C1=NC=CC (=C1) OC2=CC (=C (NC (=O) NC3=CC (=C (Cl) C=C3) C (F) (F) F) C=C2) F

Molecular Formula

C21H16Cl2F4N4O3

Additionnal Information

Regorafenib (Stivarga, BAY 73-4506) Hydrochloride is a multi-target inhibitor for VEGFR1, Murine VEGFR2/3, PDGFRβ, Kit (c-Kit), RET (c-RET) and Raf-1 with IC50 of 13 nM, 4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively.

Storage Conditions

3 years -20°C powder

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