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(R) -Nepicastat HCl

Product Specifications

CAS Number

195881-94-8

Synonyms

RS-25560-198 HCl

Target

Hydroxylase

Applications

Metabolism

Smiles

C1CC2=C (CC1N3C (=CNC3=S) CN) C=C (C=C2F) F.Cl

Molecular Formula

C14H15F2N3S.HCl

Additionnal Information

(R) -Nepicastat HCl (RS-25560-198), the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.

Storage Conditions

2 years -80 in solvent

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