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SN-38

Product Specifications

CAS Number

86639-52-3

Synonyms

NK012

Target

Topoisomerase

Applications

DNA Damage/DNA Repair

Smiles

CCC1=C2CN3C (=CC4=C (C3=O) COC (=O) C4 (CC) O) C2=NC5=C1C=C (C=C5) O

Molecular Formula

C22H20N2O5

Additionnal Information

SN-38 (NK012) is an active metabolite of CPT-11, inhibits DNA topoisomerase I, DNA synthesis and causes frequent DNA single-strand breaks. SN-38 induces autophagy.

Storage Conditions

2 years -80 in solvent

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