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SC-514

Product Specifications

CAS Number

354812-17-2

Synonyms

GK 01140

Target

IκB/IKK

Applications

NF-κB

Smiles

C1=CSC=C1C2=CC (=C (S2) C (=O) N) N

Molecular Formula

C9H8N2OS2

Additionnal Information

SC-514 (GK 01140) is an orally active, ATP-competitive IKK-2 inhibitor with IC50 of 3-12 μM, blocks NF-κB-dependent gene expression, does not inhibit other IKK isoforms or other serine-threonine and tyrosine kinases.

Storage Conditions

2 years -80 in solvent

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