Nilotinib hydrochloride monohydrate
Product Specifications
CAS Number
923288-90-8
Synonyms
Tasigna, AMN-107 hydrochloride monohydrate
Target
Bcr-Abl
Applications
Protein Tyrosine Kinase
Smiles
O.Cl.CC1=C[N] (C=N1) C2=CC (=CC (=C2) NC (=O) C3=CC (=C (C) C=C3) NC4=NC=CC (=N4) C5=CN=CC=C5) C (F) (F) F
Molecular Formula
C28H25ClF3N7O2
Additionnal Information
Nilotinib (AMN-107, Tasigna) hydrochloride monohydrate is a selective and orally bioavailable inhibitor of Bcr-Abl with IC50 < 30 nM in Murine myeloid progenitor cells. Nilotinib induces autophagy through AMPK activition.
Storage Conditions
3 years -20°C powder
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