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Daminozide

Product Specifications

CAS Number

1596-84-5

Synonyms

Aminozide, DMASA, DIMG, B 995, Alar, Kylar, B-NINE, SADH

Target

Histone Demethylase

Applications

Epigenetics

Molecular Formula

C6H12N2O3

Additionnal Information

Daminozide (Aminozide, DMASA, DIMG, B 995, Alar, Kylar, B-NINE, SADH) is a plant growth regulator that selectively inhibits human KDM2/7 histone demethylases, with IC50 of 0.55 μM for PHF8 (KDM7B), 1.5 μM for KDM2A, and 2.1 μM for KIAA1718 (KDM7A) . It shows over 100-fold selectivity for the KDM2/7 subfamily compared to other histone demethylase subfamilies, with significantly weaker activity against enzymes such as KDM3A with IC50 of 127 μM.

Storage Conditions

2 years -80 in solvent

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