β-thujaplicin

Product Specifications

CAS Number

499-44-5

Synonyms

Hinokitiol, 4-Isopropyltropolone

Target

DNA Methyltransferase

Applications

Epigenetics

Smiles

CC (C) C1=CC (=O) C (=CC=C1) O

Molecular Formula

C10H12O2

Additionnal Information

β-Thujaplicin (β-TH, Hinokitiol, 4-Isopropyltropolone) is a toxic tropolone derivative present in the heartwood of western red cedar (Thuja plicata) and is used as a preservative and antimicrobial additive in a number of commercial goods. Hinokitiol is a component of essential oils isolated from Chymacyparis obtusa, reduces Nrf2 expression, and decreases DNMT1 and UHRF1 mRNA and protein expression, with anti-infective, anti-oxidative, and anti-tumor activities.