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Jervine

Product Specifications

CAS Number

469-59-0

Synonyms

11-Ketocyclopamine

Target

Hedgehog/Smoothened

Applications

Stem Cells & Wnt

Smiles

CC1CC2C (C (C3 (O2) CCC4C5CC=C6CC (CCC6 (C5C (=O) C4=C3C) C) O) C) NC1

Molecular Formula

C27H39NO3

Additionnal Information

Jervine (11-Ketocyclopamine) is a Hedgehog signaling (IC50=500-700 nM) inhibitor that inhibits the sonic hedgehog (shh) pathway by interacting with smoothened.

Storage Conditions

2 years -80 in solvent

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