Trametinib DMSO solvate
Product Specifications
CAS Number
1187431-43-1
Synonyms
GSK1120212, JTP-74057
Target
MEK
Applications
Protein Tyrosine Kinase
Smiles
CN1C (=O) C (=C2N (C (=O) N (C3CC3) C (=O) C2=C1NC4=C (F) C=C (I) C=C4) C5=CC=CC (=C5) NC (C) =O) C.C[S] (C) =O
Molecular Formula
C28H29FIN5O5S
Additionnal Information
Trametinib DMSO solvate is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assay. Trametinib activates autophagy and induces apoptosis.
Storage Conditions
3 years -20°C powder
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