Trametinib DMSO solvate
Product Specifications
CAS Number
1187431-43-1
Synonyms
GSK1120212, JTP-74057
Target
MEK
Applications
Protein Tyrosine Kinase
Smiles
CN1C (=O) C (=C2N (C (=O) N (C3CC3) C (=O) C2=C1NC4=C (F) C=C (I) C=C4) C5=CC=CC (=C5) NC (C) =O) C.C[S] (C) =O
Molecular Formula
C28H29FIN5O5S
Additionnal Information
Trametinib DMSO solvate is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assay. Trametinib activates autophagy and induces apoptosis.
Storage Conditions
3 years -20°C powder
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![PARP1, phosphorylated (T368) (PARP1, ADPRT, PPOL, Poly [ADP-ribose] polymerase 1, ADP-ribosyltransferase diphtheria toxin-like 1, NAD (+) ADP-ribosyltransferase 1, Poly[ADP-ribose] synthase 1) (MaxLight 650) discontinued](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
039675-ML650 100 µL
PARP1, phosphorylated (T368) (PARP1, ADPRT, PPOL, Poly [ADP-ribose] polymerase 1, ADP-ribosyltransferase diphtheria toxin-like 1, NAD (+) ADP-ribosyltransferase 1, Poly[ADP-ribose] synthase 1) (MaxLight 650) discontinued
Sign In for Pricing
View Details 
TMPK-00308-01 5 µg
Nectin-4 Protein, Human, Recombinant (His & Avi)
Sign In for Pricing
View Details TMPK-00308-02 10 µg
Nectin-4 Protein, Human, Recombinant (His & Avi)
Sign In for Pricing
View Details TMPK-00308-03 20 µg
Nectin-4 Protein, Human, Recombinant (His & Avi)
Sign In for Pricing
View Details TMPK-00308-04 50 µg
Nectin-4 Protein, Human, Recombinant (His & Avi)
Sign In for Pricing
View Details