IMM-H007
Product Specifications
CAS Number
1221412-23-2
Target
AMPK
Applications
PI3K/Akt/mTOR
Smiles
CC (=O) OCC1OC (C (OC (C) =O) C1OC (C) =O) [N]2C=NC3=C (NC4=CC=CC (=C4) O) N=CN=C23
Molecular Formula
C22H23N5O8
Additionnal Information
IMM-H007, an adenosine derivative, is an activator of AMP-Activated Protein Kinase (AMPK) . IMM-H007 is a potential drug for treating cardiac dysfunction. IMM-H007 negatively regulates endothelium inflammation through inactivating NF-κB and JNK/AP1 signaling. IMM-H007 inhibits ABCA1 (ATP binding cassette subfamily a member 1) degradation and facilitates its cell-surface localization in macrophages, thereby promotes cholesterol efflux.
Storage Conditions
3 years -20°C powder
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