Auranofin
Product Specifications
CAS Number
34031-32-8
Synonyms
SKF39162
Target
Bacterial
Applications
Microbiology
Smiles
CCP (CC) CC.CC (=O) OCC1C (C (C (C (O1) [S-]) OC (=O) C) OC (=O) C) OC (=O) C.[Au+]
Molecular Formula
C20H34AuO9PS
Additionnal Information
Auranofin is an inhibitor of thioredoxin reductase (TrxR) with IC50 of 88 nM for purified H. pylori TrxR in cell-free assay. Auranofin has anti-cancer activity and can completely inhibit bacterial growth at 1.2 μM. Auranofin is an FDA-approved gold-containing compound used for the treatment of rheumatoid arthritis.
Storage Conditions
2 years -80 in solvent
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