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Diminazene Aceturate

Product Specifications

CAS Number

908-54-3

Synonyms

Diminazene diaceturate

Target

Parasite

Applications

Microbiology

Smiles

CC (=O) NCC (=O) O.CC (=O) NCC (=O) O.C1=CC (=CC=C1C (=N) N) NN=NC2=CC=C (C=C2) C (=N) N

Molecular Formula

C14H15N7.2C4H7NO3

Additionnal Information

Diminazene (Diminazene diaceturate) is a di-amidine also known as 4,4- (1-Triazene–1,3–diyl) bis (benzenecarboximidamide), used as an effective trypanocidal agent. The main biochemical mechanism of the trypanocidal actions of Diminazene aceturate is by binding to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs. Diminazene aceturate is also an angiotensin-converting enzyme 2 (ACE2) activator and has strong and potent anti-inflammatory properties.

Storage Conditions

2 years -80 in solvent

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