VPA (Valproic acid)
Product Specifications
CAS Number
99-66-1
Synonyms
2-Propylvaleric Acid, Valproate
Target
HDAC
Applications
DNA Damage/DNA Repair
Smiles
CCCC (CCC) C (=O) O
Molecular Formula
C8H16O2
Additionnal Information
VPA (Valproic acid) is a fatty acid with anticonvulsant properties used in the treatment of epilepsy. It is also a histone deacetylase (HDAC) inhibitor and is under investigation for treatment of HIV and various cancers. Valproic acid (VPA) induces autophagy and mitophagy by upregulation of BNIP3 and mitochondrial biogenesis by upregulating PGC-1α. Valproic acid activates Notch-1 signaling.
Storage Conditions
2 years -20°C liquid
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