3'-Hydroxypterostilbene

Product Specifications

CAS Number

475231-21-1

Synonyms

3'-HPT

Target

S6 Kinase

Applications

MAPK

Smiles

COC1=CC (=CC (=C1) C=CC2=CC (=C (C=C2) O) O) OC

Molecular Formula

C16H16O4

Additionnal Information

3'-Hydroxypterostilbene (3'-HPT) is one of the active constituents of Sphaerophysa salsula and Pterocarpus marsupium which may be useful in treating different types of haematological malignancies. 3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells (IC50s of 9.0, 40.2, and 70.9 μM for COLO 205, HCT-116, and HT-29 cells, respectively) by inducing apoptosis and autophagy. 3'-Hydroxypterostilbene inhibits the PI3K/Akt/mTOR/p70S6K, and p38MAPK pathways and activates the ERK1/2, JNK1/2 MAPK pathways.