Hydroxy Camptothecine
Product Specifications
CAS Number
64439-81-2
Synonyms
10-Hydroxycamptothecin, Hydroxycamptothecine
Target
Topoisomerase
Applications
DNA Damage/DNA Repair
Smiles
CCC1 (C2=C (COC1=O) C (=O) N3CC4=C (C3=C2) N=C5C=CC (=CC5=C4) O) O
Molecular Formula
C20H16N2O5
Additionnal Information
Hydroxy Camptothecine (10-Hydroxycamptothecin, Hydroxycamptothecine) is a cell-permeable powerful DNA topoisomerase I inhibitor. It has selective inhibitory effect on the phosphorylation of histone H1 and H3, but less effect on other histones.
Storage Conditions
2 years -80 in solvent
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