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Hydroxy Camptothecine

Product Specifications

CAS Number

64439-81-2

Synonyms

10-Hydroxycamptothecin, Hydroxycamptothecine

Target

Topoisomerase

Applications

DNA Damage/DNA Repair

Smiles

CCC1 (C2=C (COC1=O) C (=O) N3CC4=C (C3=C2) N=C5C=CC (=CC5=C4) O) O

Molecular Formula

C20H16N2O5

Additionnal Information

Hydroxy Camptothecine (10-Hydroxycamptothecin, Hydroxycamptothecine) is a cell-permeable powerful DNA topoisomerase I inhibitor. It has selective inhibitory effect on the phosphorylation of histone H1 and H3, but less effect on other histones.

Storage Conditions

2 years -80 in solvent

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