Jatrorrhizine
Product Specifications
CAS Number
3621-38-3
Synonyms
Neprotin, Yatrorizine
Target
AChR
Applications
Neuronal Signaling
Smiles
COC1=C (C2=C[N+]3=C (C=C2C=C1) C4=CC (=C (C=C4CC3) O) OC) OC
Molecular Formula
C20H20NO4
Additionnal Information
Jatrorrhizine (Neprotin, Yatrorizine), one of the active constituents of Coptis chinensis Franch, has multiple bioactivities, such as hypoglycemic, antimicrobial, and antioxidant activities. It is an inhibitor of AChE with IC50 of 872 nM and demonstrates >115-fold selectivity for AChE over BuChE.
Storage Conditions
2 years -80 in solvent
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