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Jatrorrhizine

Product Specifications

CAS Number

3621-38-3

Synonyms

Neprotin, Yatrorizine

Target

AChR

Applications

Neuronal Signaling

Smiles

COC1=C (C2=C[N+]3=C (C=C2C=C1) C4=CC (=C (C=C4CC3) O) OC) OC

Molecular Formula

C20H20NO4

Additionnal Information

Jatrorrhizine (Neprotin, Yatrorizine), one of the active constituents of Coptis chinensis Franch, has multiple bioactivities, such as hypoglycemic, antimicrobial, and antioxidant activities. It is an inhibitor of AChE with IC50 of 872 nM and demonstrates >115-fold selectivity for AChE over BuChE.

Storage Conditions

2 years -80 in solvent

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