Euphorbiasteroid

Product Specifications

CAS Number

28649-59-4

Synonyms

Euphorbia factor L1

Target

AMPK

Applications

PI3K/Akt/mTOR

Smiles

CC1CC2 (C (C1OC (=O) CC3=CC=CC=C3) C (C4 (CCC5C (C5 (C) C) C=C (C2=O) C) CO4) OC (=O) C) OC (=O) C

Molecular Formula

C32H40O8

Additionnal Information

Euphorbiasteroid (Euphorbia factor L1), a component of Euphorbia lathyris L., inhibits adipogenesis of 3T3-L1 cells through activation of the AMPK pathway and induces HL-60 cells to apoptosis via promoting Bcl-2/Bax apoptotic signaling pathway in a dose-dependent manner. Euphorbiasteroid is a tricyclic diperpene of Euphorbia lathyris L., inhibits tyrosinase, and increases the phosphorylation of AMPK, with anti-cancer, anti-virus, anti-obesity and multidrug resistance-modulating effect.