Dehydroevodiamine

Product Specifications

CAS Number

67909-49-3

Synonyms

DHED

Target

ROS

Applications

NF-κB

Smiles

CN1C2=CC=CC=C2C (=O) N3C1=C4C (=C5C=CC=CC5=N4) CC3

Molecular Formula

C19H15N3O

Additionnal Information

Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant, inhibition of nitric oxide production and cerebral blood flow enhancing activities. Dehydroevodiamine inhibits LPS-induced iNOS, COX-2, prostaglandin E2 (PGE2) and nuclear factor-kappa B (NF-κB) expression in murine macrophage cells.