Scutellarin

Product Specifications

CAS Number

27740-01-8

Synonyms

Breviscapine, Breviscapin, Scutellarein-7-glucuronide

Target

STAT

Applications

Apoptosis

Smiles

C1=CC (=CC=C1C2=CC (=O) C3=C (C (=C (C=C3O2) OC4C (C (C (C (O4) C (=O) O) O) O) O) O) O) O

Molecular Formula

C21H18O12

Additionnal Information

Scutellarin (Breviscapine, Breviscapin, Scutellarein-7-glucuronide), the major active principal flavonoids extracted from the Chinese herbal medicines Scutellaria baicalensis and Erigeron breviscapus (Vant.) Hand-Mazz, has many pharmacological effects, such as antioxidant, antitumor, antiviral, and antiinflammatory activities. Scutellarin can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts.