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NEM (N-Ethylmaleimide)

Product Specifications

CAS Number

128-53-0

Target

Cysteine Protease

Applications

Proteases

Smiles

CCN1C (=O) C=CC1=O

Molecular Formula

C6H7NO2

Additionnal Information

NEM (N-Ethylmaleimide) is an organic compound that is derived from maleic acid. It is an irreversible inhibitor of all cysteine peptidases, with alkylation occurring at the active site thiol group. N-Ethylmaleimide (NEM) inactivates endogenous deubiquitinating enzymes (DUBs) . N-Ethylmaleimide (NEM) specifically inhibits phosphate transport in mitochondria.

Storage Conditions

2 years -80 in solvent

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