Sarsasapogenin
Product Specifications
CAS Number
126-19-2
Synonyms
Parigenin
Target
ROS
Applications
NF-κB
Smiles
CC1CCC2 (C (C3C (O2) CC4C3 (CCC5C4CCC6C5 (CCC (C6) O) C) C) C) OC1
Molecular Formula
C27H44O3
Additionnal Information
Sarsasapogenin (SAR, Parigenin) is a steroidal sapogenin. It can provoke the generation of reactive oxygen species and activate unfolded protein response (UPR) signaling pathways. SAR potently inhibits NF-κB and MAPK activation, as well as IRAK1, TAK1, and IκBα phosphorylation in LPS-stimulated macrophages.
Storage Conditions
2 years -80 in solvent
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