BMS-986020
Product Specifications
CAS Number
1257213-50-5
Synonyms
AM152, AP-3152 free acid
Target
LPA Receptor
Applications
GPCR & G Protein
Smiles
CC (OC (=O) NC1=C (ON=C1C) C2=CC=C (C=C2) C3=CC=C (C=C3) C4 (CC4) C (O) =O) C5=CC=CC=C5
Molecular Formula
C29H26N2O5
Additionnal Information
BMS-986020 (AM152, AP-3152 free acid) is a potent and selective antagonist of lysophosphatidic acid receptor 1 (LPA1) . BMS-986020 inhibits bile acid and phospholipid transporters with IC50 of 4.8 μM, 6.2 μM, and 7.5 μM for BSEP, MRP4, and MDR3, respectively. BMS-986020 has the potential for the treatment of idiopathic pulmonary fibrosis (IPF) .
Storage Conditions
3 years -20°C powder
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