Brequinar Sodium
Product Specifications
CAS Number
96201-88-6
Synonyms
Bipenquinate, BRQ, DUP-785, NSC 368390
Target
Dehydrogenase
Applications
Metabolism
Smiles
CC1=C (C (=O) O[Na]) C2=CC (=CC=C2N=C1C3=CC=C (C=C3) C4=C (F) C=CC=C4) F
Molecular Formula
C23H14F2NNaO2
Additionnal Information
Brequinar Sodium (Bipenquinate, BRQ, DUP-785, NSC 368390) is a potent and selective dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of ~20 nM and triggers differentiation in the ER-HoxA9, U937, and THP1 cells with ED50 of ~1 μM.
Storage Conditions
3 years -20°C powder
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