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Golidocitinib (AZD4205)

Product Specifications

CAS Number

2091134-68-6

Target

JAK

Applications

Angiogenesis

Additionnal Information

Golidocitinib (AZD4205) (Compound 21) is a highly selective and potent inhibitor of Janus kinase 1 (JAK1), with an IC50 of 0.07 μM for JAK1 and much weaker inhibition of JAK2 (IC50 > 15 μM) . It also exhibits potent antitumor effects in NSCLC xenograft models in preclinical studies.

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