Metarrestin
Product Specifications
CAS Number
1443414-10-5
Synonyms
ML246
Target
DNA/RNA Synthesis
Applications
Cell Cycle
Smiles
OC1CCC (CC1) N2C=NC3=C (C2=N) C (=C ([N]3CC4=CC=CC=C4) C5=CC=CC=C5) C6=CC=CC=C6
Molecular Formula
C31H30N4O
Additionnal Information
Metarrestin is an orally active and specific perinucleolar compartment (PNC) inhibitor that disrupts the nucleolar structure and inhibits RNA polymerase (Pol) I transcription. Metarrestin blocks metastatic development and extends survival in mouse cancer models.
Storage Conditions
3 years -20°C powder
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