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Metarrestin

Product Specifications

CAS Number

1443414-10-5

Synonyms

ML246

Target

DNA/RNA Synthesis

Applications

Cell Cycle

Smiles

OC1CCC (CC1) N2C=NC3=C (C2=N) C (=C ([N]3CC4=CC=CC=C4) C5=CC=CC=C5) C6=CC=CC=C6

Molecular Formula

C31H30N4O

Additionnal Information

Metarrestin is an orally active and specific perinucleolar compartment (PNC) inhibitor that disrupts the nucleolar structure and inhibits RNA polymerase (Pol) I transcription. Metarrestin blocks metastatic development and extends survival in mouse cancer models.

Storage Conditions

3 years -20°C powder

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