Desoxyrhaponticin

Product Specifications

CAS Number

30197-14-9

Synonyms

DC, DES

Target

Fatty Acid Synthase

Applications

Metabolism

Smiles

COC1=CC=C (C=C1) /C=C/C2=CC (=CC (=C2) O) OC3OC (CO) C (O) C (O) C3O

Molecular Formula

C21H24O8

Additionnal Information

Desoxyrhaponticin (DC, DES), a stilbene glycoside from Rheum tanguticum Maxim. ex Balf. (rhubarb) which is a traditional Chinese nutritional food, is a fatty acid synthase (FAS/FASN) inhibitor. Desoxyrhaponticin (DC, DES) is also a competitive inhibitor of glucose uptake with IC50 of 148.3 μM and 30.9 μM in rabbit intestinal membrane vesicles and in rat everted gut sleeves, respectively. Desoxyrhaponticin has apoptotic effect on human cancer cells.