Desoxyrhaponticin
Product Specifications
CAS Number
30197-14-9
Synonyms
DC, DES
Target
Fatty Acid Synthase
Applications
Metabolism
Smiles
COC1=CC=C (C=C1) /C=C/C2=CC (=CC (=C2) O) OC3OC (CO) C (O) C (O) C3O
Molecular Formula
C21H24O8
Additionnal Information
Desoxyrhaponticin (DC, DES), a stilbene glycoside from Rheum tanguticum Maxim. ex Balf. (rhubarb) which is a traditional Chinese nutritional food, is a fatty acid synthase (FAS/FASN) inhibitor. Desoxyrhaponticin (DC, DES) is also a competitive inhibitor of glucose uptake with IC50 of 148.3 μM and 30.9 μM in rabbit intestinal membrane vesicles and in rat everted gut sleeves, respectively. Desoxyrhaponticin has apoptotic effect on human cancer cells.
Storage Conditions
3 years -20°C powder
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