Hispidulin
Product Specifications
CAS Number
1447-88-7
Synonyms
Dinatin
Target
Pim
Applications
JAK/STAT
Smiles
COC1=C (O) C=C2OC (=CC (=O) C2=C1O) C3=CC=C (O) C=C3
Molecular Formula
C16H12O6
Additionnal Information
Hispidulin (Dinatin), an active natrual ingredient in a number of traditional Chinese medicinal herbs, exhibits inhibitory activity against the oncogenic protein kinase Pim-1 with IC50 of 2.71 μM. Hispidulin induces apoptosis through mitochondrial dysfunction and inhibition of P13k/Akt signalling pathway in HepG2 cancer cells. Hispidulin exerts anti-osteoporotic and bone resorption attenuating effects via activating the AMPK signaling pathway.
Storage Conditions
3 years -20°C powder
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